Nuwe resepte

Navorsers ontdek karsinogene in alkoholiese drank

Navorsers ontdek karsinogene in alkoholiese drank

Wetenskaplikes sê meer as 4 drankies per dag neem die risiko van kanker op

Passievolle wyndrinkers is bewus van die baie stowwe wat in hul wyne voorkom. Dinge soos sure, tanniene en resveratrol dryf in elke glas rond. 'N Nuwe studie het bevind dat kankerverwekkende middels ook in die wyne voorkom, volgens WineSpectator.com.

Die studie, uitgevoer deur navorsers aan die Dresden Universiteit van Tegnologie, het meer as spoorvlakke van karsinogene in 'n steekproef kommersiële alkoholiese drank gevind, insluitend die arseen, benseen, formaldehied en lood. Die wetenskaplikes het bevind dat etanol, die karsinogeen met die hoogste konsentrasie in alkoholiese drank, drie en 'n half keer meer kans het om kanker te veroorsaak by diegene wat vier of meer drankies per dag drink as by diegene wat minder het, volgens die artikel op WineSpectator. com.

Hoewel die studie getoon het dat ligte tot matige alkoholgebruik min risiko vir kanker dra, het Dirk Lachenmeier, 'n epidemioloog en die hoofskrywer van die studie, gesê dat verbruikers steeds bewus moet wees van die inhoud van hul drankies. Omdat rooiwyn bekend is vir sy gesonde eienskappe, moes Lachenmeier kritici van sy bevindings nogal reageer.

Van WineSpectator.com:

"Een argument teen die wetenskaplikes se standpunt is dat sommige studies bewyse gevind het dat verbindings in rooiwyn die risiko van borskanker kan verlaag. Lachenmeier het toegegee dat rooiwyn stowwe teen kanker kan voorkom, maar dit word nie in die huidige studie gemeet nie. dat die gevolgtrekkings voorlopig veronderstelling bly. 'Die meeste studies oor sulke verbindings, soos resveratrol, is gebaseer op in vitro-resultate, wat nie bruikbaar is vir kwantitatiewe dosis-reaksie-analises soos in ons studie uitgevoer nie,' het hy gesê.

- Wayne Stainrook, Glad


Navorsers ontdek dat die mens se liggaam alkohol produseer

(CNN) - Toe 'n man in Noord -Carolina afgetrek word omdat hy vermoedelik dronk bestuur het, het die polisie hom nie geglo toe hy gesê het dat hy nie alkohol gehad het nie.

Die man, destyds in die laat veertigerjare, het geweier om 'n asemtoets te neem en is na 'n hospitaal geneem, waar sy aanvanklike bloedalkoholvlak 0.2% was - ongeveer 2.5 keer die wettige limiet en die ekwivalent van die gebruik van 10 drankies n uur. Ten spyte daarvan dat die man op en af ​​sweer dat hy niks gehad het om te drink nie, het dokters hom ook nie geglo nie.

Maar navorsers van die Richmond University Medical Center in New York het uiteindelik ontdek dat die man die waarheid praat. Hy het nie bier of skemerkelkies laat sak nie - in plaas daarvan was daar gis in sy ingewande wat waarskynlik koolhidrate in die kos wat hy geëet het, kon verander na alkohol.

Met ander woorde, sy liggaam was besig om bier te brou.

Die bevindings is gerapporteer in 'n studie in BMJ Open Gastroenterology. Die man, wie se identiteit nie bekend gemaak is nie, het 'n selde gediagnoseerde mediese toestand genaamd auto-brouery sindroom (ABS), ook bekend as dermfermentasiesindroom.

Darmgistingsindroom kom voor wanneer gis in die spysverteringskanaal veroorsaak dat die liggaam koolhidrate wat deur voedsel ingeneem word, omskakel in alkohol. Die proses vind gewoonlik plaas in die boonste GI -kanaal, wat die maag en die eerste deel van die dunderm insluit.

"Hierdie pasiënte het presies dieselfde implikasies van alkoholisme: die reuk, die asemhaling, slaperigheid, veranderings in die gang," het Fahad Malik, hoofskrywer van die studie en die inwoner van die interne geneeskunde aan die Universiteit van Alabama in Birmingham, aan CNN gesê. 'Hulle sal verskyn as iemand wat dronk is deur alkohol, maar die enigste verskil hier is dat hierdie pasiënte met antifungale medisyne behandel kan word.'

Navorsers het hom met antifungale medisyne behandel

Dinge was nie dieselfde vir die man nadat hy 'n kursus antibiotika voltooi het om 'n duimbesering te behandel nie. Sy persoonlikheid het begin verander, het navorsers in die studie geskryf, en hy het episodes van depressie, 'breinmis', geheueverlies en aggressiewe gedrag ervaar wat vir hom uiters karaktervol was.

Drie jaar later, na sy vermeende dronkbestuur -arrestasie, het die man se tante 'n blaasmasjien gekoop om sy alkoholvlakke op te teken. Sy het gehoor van 'n soortgelyke geval wat suksesvol deur 'n dokter in Ohio behandel is en haar neef oortuig om ook daar behandeling te soek.

Sy basiese laboratoriumtoetse was normaal. Maar dokters het twee stamme gis in sy stoelgang gevind: Saccharomyces cerevisiae, 'n gis wat algemeen gebruik word by bierbrou, wynmaak en bak, asook 'n ander swam.

Die man is suksesvol in die kliniek in Ohio behandel en aangesê om by 'n streng koolhidraatvrye dieet te bly, asook spesiale aanvullings. Maar na 'n paar weke het sy simptome weer begin opvlam. Hierdie keer het dit gelyk asof geen behandeling werk nie, ondanks besoeke aan talle mediese spesialiste.

Op 'n stadium het die man so dronk geword dat hy geval en bloeding in sy brein ondervind het. Hy is na 'n neurochirurgiese sentrum geneem waar hy binne 10 dae spontaan herstel het, het navorsers gesê.

'In hierdie instelling het sy bloedalkoholvlakke gewissel van 50 tot 400 mg/dL,' het die navorsers geskryf. "Ook hier het die mediese personeel geweier om te glo dat hy ondanks sy volgehoue ​​ontkenning nie alkohol gedrink het nie."

Uiteindelik het die man hulp by 'n aanlyn ondersteuningsgroep gesoek en met die navorsers van die Richmond University Medical Center in verbinding getree, wat in die studie gesê het dat hulle glo dat die antibiotika wat hy jare gelede geneem het, sy derm mikrobioom verander en dat swamme in sy spysverteringskanaal.

Die navorsers het daarna antifungale terapieë en probiotika gebruik om die bakterieë in sy ingewande te normaliseer, 'n behandeling wat hy voortgesit het. En afgesien van 'n terugval wat plaasgevind het nadat hy pizza en koeldrank gebyt het sonder om die navorsers te vertel, lyk dit asof dit werk.

En hy kan weer pizza eet.

'Ongeveer 1,5 jaar later bly hy asimptomaties en het hy sy vorige lewenstyl hervat, insluitend die eet van 'n normale dieet, terwyl hy nog steeds sy asemhaling alkohol sporadies nagaan', het die skrywers in die studie geskryf.

Die toestand word selde gediagnoseer

Daar is slegs 'n paar studies wat gevalle van dermfermentasiesindroom beskryf en die toestand word selde gediagnoseer, het Malik gesê. In die verlede is dit selfs as 'n mite beskou.

Darmgistesindroom word in 1912 beskryf as 'kiemkoolhidraatfermentasie', en is in die 1930's en 1940's bestudeer as 'n bydraende faktor tot vitamientekorte en prikkelbare dermsindroom. 'N Groep van 20 tot 30 gevalle het in die sewentigerjare in Japan verskyn en die eerste Amerikaanse gevalle is ongeveer 10 jaar later aangemeld.

Daar was die afgelope paar jaar 'n handjievol aangemelde gevalle. 'N 2013-studie beskryf 'n geval van 'n 61-jarige man wat jare lank altyd dronk was voordat hy met die dermfermentasiesindroom gediagnoseer is. In 2015 het 'n DUI van 'n vrou in die staat New York ontslaan nadat sy bewys gelewer het dat sy die toestand het.

Die skrywers van die studie van die Richmond University Medical Center beveel dokters aan om ondersoek in te stel na die toestand, veral as 'n pasiënt 'n verhoogde alkoholgehalte in die bloed toon ondanks die ontkenning dat hy alkohol gebruik het.

Die vroeë tekens van dermfermentasiesindroom kan gemoedsveranderinge, delirium en breinmis insluit, het die navorsers geskryf, selfs voordat 'n pasiënt simptome van alkoholverslawing begin toon.

Die studie sê meer navorsing moet gedoen word oor die gebruik van probiotika as 'n behandeling vir die toestand.

'Dit is 'n toestand wat behandel kan word met dieetaanpassings, gepaste antifungale terapie en moontlik probiotika,' het die navorsers geskryf. "Die gebruik van probiotika en fekale mikrobiota -oorplanting kan oorweeg word vir toekomstige studies."

Die-CNN-draad
™ en amp © 2019 Cable News Network, Inc., 'n WarnerMedia -onderneming. Alle regte voorbehou.


Navorsers ontdek dat die mens se liggaam alkohol produseer

(CNN) - Toe 'n man in Noord -Carolina afgetrek word omdat hy vermoedelik dronk bestuur het, het die polisie hom nie geglo toe hy gesê het dat hy nie alkohol gehad het nie.

Die man, destyds in die laat veertigerjare, het geweier om 'n asemtoets te neem en is na 'n hospitaal geneem, waar sy aanvanklike bloedalkoholvlak 0.2% was - ongeveer 2.5 keer die wettige limiet en die ekwivalent van die gebruik van 10 drankies n uur. Ten spyte daarvan dat die man op en af ​​sweer dat hy niks gehad het om te drink nie, het dokters hom ook nie geglo nie.

Maar navorsers van die Richmond University Medical Center in New York het uiteindelik ontdek dat die man die waarheid praat. Hy het nie bier of skemerkelkies laat sak nie - in plaas daarvan was daar gis in sy ingewande wat waarskynlik koolhidrate in die kos wat hy geëet het, kon verander na alkohol.

Met ander woorde, sy liggaam was besig om bier te brou.

Die bevindings is gerapporteer in 'n studie in BMJ Open Gastroenterology. Die man, wie se identiteit nie bekend gemaak is nie, het 'n selde gediagnoseerde mediese toestand genaamd auto-brouery sindroom (ABS), ook bekend as dermfermentasiesindroom.

Darmgistingsindroom kom voor wanneer gis in die spysverteringskanaal veroorsaak dat die liggaam koolhidrate wat deur voedsel ingeneem word, omskakel in alkohol. Die proses vind gewoonlik plaas in die boonste GI -kanaal, wat die maag en die eerste deel van die dunderm insluit.

"Hierdie pasiënte het presies dieselfde implikasies van alkoholisme: die reuk, die asemhaling, slaperigheid, gangveranderinge," het Fahad Malik, hoofskrywer van die studie en die hoof inwoner van die interne geneeskunde aan die Universiteit van Alabama in Birmingham, aan CNN gesê. 'Hulle sal verskyn as iemand wat dronk is deur alkohol, maar die enigste verskil hier is dat hierdie pasiënte met antifungale medisyne behandel kan word.'

Navorsers het hom met antifungale medisyne behandel

Dinge was nie dieselfde vir die man nadat hy 'n kursus antibiotika voltooi het om 'n duimbesering te behandel nie. Sy persoonlikheid het begin verander, het navorsers in die studie geskryf, en hy het episodes van depressie, 'breinmis', geheueverlies en aggressiewe gedrag ervaar wat vir hom uiters karaktervol was.

Drie jaar later, na sy vermeende dronkbestuur -arrestasie, het die man se tante 'n blaasmasjien gekoop om sy alkoholvlakke op te teken. Sy het gehoor van 'n soortgelyke geval wat suksesvol deur 'n dokter in Ohio behandel is en haar neef oortuig om ook daar behandeling te soek.

Sy basiese laboratoriumtoetse was normaal. Maar dokters het twee stamme gis in sy stoelgang gevind: Saccharomyces cerevisiae, 'n gis wat algemeen gebruik word by bierbrou, wynmaak en bak, asook 'n ander swam.

Die man is suksesvol in die kliniek in Ohio behandel en aangesê om by 'n streng koolhidraatvrye dieet te bly, asook spesiale aanvullings. Maar na 'n paar weke het sy simptome weer begin opvlam. Hierdie keer het dit gelyk asof geen behandeling werk nie, ondanks besoeke aan talle mediese spesialiste.

Op 'n stadium het die man so dronk geword dat hy geval en bloeding in sy brein ondervind het. Hy is na 'n neurochirurgiese sentrum geneem waar hy binne 10 dae spontaan herstel het, het navorsers gesê.

'In hierdie instelling het sy bloedalkoholvlakke gewissel van 50 tot 400 mg/dL,' het die navorsers geskryf. "Ook hier het die mediese personeel geweier om te glo dat hy ondanks sy volgehoue ​​ontkenning nie alkohol gedrink het nie."

Uiteindelik het die man hulp by 'n aanlyn ondersteuningsgroep gesoek en met die navorsers van die Richmond University Medical Center in verbinding getree, wat in die studie gesê het dat hulle glo dat die antibiotika wat hy jare gelede geneem het, sy derm mikrobioom verander en dat swamme in sy spysverteringskanaal.

Die navorsers het daarna antifungale terapieë en probiotika gebruik om die bakterieë in sy ingewande te normaliseer, 'n behandeling wat hy voortgesit het. En afgesien van 'n terugval wat plaasgevind het nadat hy pizza en koeldrank gebyt het sonder om die navorsers te vertel, lyk dit asof dit werk.

En hy kan weer pizza eet.

'Ongeveer 1,5 jaar later bly hy asimptomaties en het hy sy vorige lewenstyl hervat, insluitend die eet van 'n normale dieet, terwyl hy nog steeds sy asemhaling alkohol sporadies nagaan', het die skrywers in die studie geskryf.

Die toestand word selde gediagnoseer

Daar is slegs 'n paar studies wat gevalle van dermfermentasiesindroom beskryf en die toestand word selde gediagnoseer, het Malik gesê. In die verlede is dit selfs as 'n mite beskou.

Darmgistesindroom word in 1912 beskryf as 'kiemkoolhidraatfermentasie', en is in die 1930's en 1940's bestudeer as 'n bydraende faktor tot vitamientekorte en prikkelbare dermsindroom. 'N Groep van 20 tot 30 gevalle het in die sewentigerjare in Japan verskyn en die eerste Amerikaanse gevalle is ongeveer 10 jaar later aangemeld.

Daar was die afgelope paar jaar 'n handjievol aangemelde gevalle. 'N 2013-studie beskryf 'n geval van 'n 61-jarige man wat jare lank altyd dronk was voordat hy met die dermfermentasiesindroom gediagnoseer is. In 2015 het 'n DUI van 'n vrou in die staat New York ontslaan nadat sy bewys gelewer het dat sy die toestand het.

Die skrywers van die studie van die Richmond University Medical Center beveel dokters aan om ondersoek in te stel na die toestand, veral as 'n pasiënt 'n verhoogde alkoholgehalte in die bloed toon ondanks die ontkenning dat hy alkohol gebruik het.

Die vroeë tekens van dermfermentasiesindroom kan gemoedsveranderinge, delirium en breinmis insluit, het die navorsers geskryf, selfs voordat 'n pasiënt simptome van alkoholverslawing begin toon.

Die studie sê meer navorsing moet gedoen word oor die gebruik van probiotika as 'n behandeling vir die toestand.

'Dit is 'n toestand wat behandel kan word met dieetaanpassings, gepaste antifungale terapie en moontlik probiotika,' het die navorsers geskryf. "Die gebruik van probiotika en fekale mikrobiota -oorplanting kan oorweeg word vir toekomstige studies."

Die-CNN-draad
™ en amp © 2019 Cable News Network, Inc., 'n WarnerMedia -onderneming. Alle regte voorbehou.


Navorsers ontdek dat die mens se liggaam alkohol produseer

(CNN) - Toe 'n man in Noord -Carolina afgetrek word omdat hy vermoedelik dronk bestuur het, het die polisie hom nie geglo toe hy gesê het dat hy nie alkohol gehad het nie.

Die man, destyds in die laat veertigerjare, het geweier om 'n asemtoets te neem en is na 'n hospitaal geneem, waar sy aanvanklike bloedalkoholvlak 0.2% was - ongeveer 2.5 keer die wettige limiet en die ekwivalent van die gebruik van 10 drankies n uur. Ten spyte daarvan dat die man op en af ​​sweer dat hy niks gehad het om te drink nie, het dokters hom ook nie geglo nie.

Maar navorsers van die Richmond University Medical Center in New York het uiteindelik ontdek dat die man die waarheid praat. Hy het nie bier of skemerkelkies laat sak nie - in plaas daarvan was daar gis in sy ingewande wat waarskynlik koolhidrate in die kos wat hy geëet het, kon verander na alkohol.

Met ander woorde, sy liggaam was besig om bier te brou.

Die bevindings is gerapporteer in 'n studie in BMJ Open Gastroenterology. Die man, wie se identiteit nie bekend gemaak is nie, het 'n selde gediagnoseerde mediese toestand genaamd auto-brouery sindroom (ABS), ook bekend as dermfermentasiesindroom.

Darmgistingsindroom kom voor wanneer gis in die spysverteringskanaal veroorsaak dat die liggaam koolhidrate wat deur voedsel ingeneem word, omskakel in alkohol. Die proses vind gewoonlik plaas in die boonste GI -kanaal, wat die maag en die eerste deel van die dunderm insluit.

"Hierdie pasiënte het presies dieselfde implikasies van alkoholisme: die reuk, die asemhaling, slaperigheid, veranderings in die gang," het Fahad Malik, hoofskrywer van die studie en die inwoner van die interne geneeskunde aan die Universiteit van Alabama in Birmingham, aan CNN gesê. 'Hulle sal verskyn as iemand wat dronk is deur alkohol, maar die enigste verskil hier is dat hierdie pasiënte met antifungale medisyne behandel kan word.'

Navorsers het hom met antifungale medisyne behandel

Dinge was nie dieselfde vir die man nadat hy 'n kursus antibiotika voltooi het om 'n duimbesering te behandel nie. Sy persoonlikheid het begin verander, het navorsers in die studie geskryf, en hy het episodes van depressie, 'breinmis', geheueverlies en aggressiewe gedrag ervaar wat vir hom uiters karaktervol was.

Drie jaar later, na sy vermeende dronkbestuur -arrestasie, het die man se tante 'n blaasmasjien gekoop om sy alkoholvlakke op te teken. Sy het gehoor van 'n soortgelyke geval wat suksesvol deur 'n dokter in Ohio behandel is en haar neef oortuig om ook daar behandeling te soek.

Sy basiese laboratoriumtoetse was normaal. Maar dokters het twee stamme gis in sy stoelgang gevind: Saccharomyces cerevisiae, 'n gis wat algemeen gebruik word by bierbrou, wynmaak en bak, asook 'n ander swam.

Die man is suksesvol in die kliniek in Ohio behandel en aangesê om by 'n streng koolhidraatvrye dieet te bly, asook spesiale aanvullings. Maar na 'n paar weke het sy simptome weer begin opvlam. Hierdie keer het dit gelyk asof geen behandeling werk nie, ondanks besoeke aan talle mediese spesialiste.

Op 'n stadium het die man so dronk geword dat hy geval en bloeding in sy brein ondervind het. Hy is na 'n neurochirurgiese sentrum geneem waar hy binne 10 dae spontaan herstel het, het navorsers gesê.

'In hierdie instelling het sy bloedalkoholvlakke gewissel van 50 tot 400 mg/dL,' het die navorsers geskryf. "Ook hier het die mediese personeel geweier om te glo dat hy ondanks sy volgehoue ​​ontkenning nie alkohol gedrink het nie."

Uiteindelik het die man hulp by 'n aanlyn ondersteuningsgroep gesoek en met die navorsers van die Richmond University Medical Center in verbinding getree, wat in die studie gesê het dat hulle glo dat die antibiotika wat hy jare gelede geneem het, sy derm mikrobioom verander en dat swamme in sy spysverteringskanaal.

Die navorsers het daarna antifungale terapieë en probiotika gebruik om die bakterieë in sy ingewande te normaliseer, 'n behandeling wat hy voortgesit het. En afgesien van 'n terugval wat plaasgevind het nadat hy pizza en koeldrank gebyt het sonder om die navorsers te vertel, lyk dit asof dit werk.

En hy kan weer pizza eet.

'Ongeveer 1,5 jaar later bly hy asimptomaties en het hy sy vorige lewenstyl hervat, insluitend die eet van 'n normale dieet, terwyl hy nog steeds sy asemhaling alkohol sporadies nagaan', het die skrywers in die studie geskryf.

Die toestand word selde gediagnoseer

Daar is slegs 'n paar studies wat gevalle van dermfermentasiesindroom beskryf en die toestand word selde gediagnoseer, het Malik gesê. In die verlede is dit selfs as 'n mite beskou.

Darmgistesindroom word in 1912 beskryf as 'kiemkoolhidraatfermentasie', en is in die 1930's en 1940's bestudeer as 'n bydraende faktor tot vitamientekorte en prikkelbare dermsindroom. 'N Groep van 20 tot 30 gevalle het in die sewentigerjare in Japan verskyn en die eerste Amerikaanse gevalle is ongeveer 10 jaar later aangemeld.

Daar was die afgelope paar jaar 'n handjievol aangemelde gevalle. 'N 2013-studie beskryf 'n geval van 'n 61-jarige man wat jare lank altyd dronk was voordat hy met die dermfermentasiesindroom gediagnoseer is. In 2015 het 'n DUI van 'n vrou in die staat New York ontslaan nadat sy bewys gelewer het dat sy die toestand het.

Die skrywers van die studie van die Richmond University Medical Center beveel dokters aan om ondersoek in te stel na die toestand, veral as 'n pasiënt 'n verhoogde alkoholgehalte in die bloed toon ondanks die ontkenning dat hy alkohol gebruik het.

Die vroeë tekens van dermfermentasiesindroom kan gemoedsveranderinge, delirium en breinmis insluit, het die navorsers geskryf, selfs voordat 'n pasiënt simptome van alkoholverslawing begin toon.

Die studie sê meer navorsing moet gedoen word oor die gebruik van probiotika as 'n behandeling vir die toestand.

'Dit is 'n toestand wat behandel kan word met dieetaanpassings, gepaste antifungale terapie en moontlik probiotika,' het die navorsers geskryf. "Die gebruik van probiotika en fekale mikrobiota -oorplanting kan oorweeg word vir toekomstige studies."

Die-CNN-draad
™ en amp © 2019 Cable News Network, Inc., 'n WarnerMedia -onderneming. Alle regte voorbehou.


Navorsers ontdek dat die mens se liggaam alkohol produseer

(CNN) - Toe 'n man in Noord -Carolina afgetrek word omdat hy vermoedelik dronk bestuur het, het die polisie hom nie geglo toe hy gesê het dat hy nie alkohol gehad het nie.

Die man, destyds in die laat veertigerjare, het geweier om 'n asemtoets te neem en is na 'n hospitaal geneem, waar sy aanvanklike bloedalkoholvlak 0.2% was - ongeveer 2.5 keer die wettige limiet en die ekwivalent van die gebruik van 10 drankies n uur. Ten spyte daarvan dat die man op en af ​​sweer dat hy niks gehad het om te drink nie, het dokters hom ook nie geglo nie.

Maar navorsers van die Richmond University Medical Center in New York het uiteindelik ontdek dat die man die waarheid praat. Hy het nie bier of skemerkelkies laat sak nie - in plaas daarvan was daar gis in sy ingewande wat waarskynlik koolhidrate in die kos wat hy geëet het, kon verander na alkohol.

Met ander woorde, sy liggaam was besig om bier te brou.

Die bevindings is gerapporteer in 'n studie in BMJ Open Gastroenterology. Die man, wie se identiteit nie bekend gemaak is nie, het 'n selde gediagnoseerde mediese toestand genaamd auto-brouery sindroom (ABS), ook bekend as dermfermentasiesindroom.

Darmgistingsindroom kom voor wanneer gis in die spysverteringskanaal veroorsaak dat die liggaam koolhidrate wat deur voedsel ingeneem word, omskakel in alkohol. Die proses vind gewoonlik plaas in die boonste GI -kanaal, wat die maag en die eerste deel van die dunderm insluit.

"Hierdie pasiënte het presies dieselfde implikasies van alkoholisme: die reuk, die asemhaling, slaperigheid, gangveranderinge," het Fahad Malik, hoofskrywer van die studie en die hoof inwoner van die interne geneeskunde aan die Universiteit van Alabama in Birmingham, aan CNN gesê. 'Hulle sal verskyn as iemand wat dronk is deur alkohol, maar die enigste verskil hier is dat hierdie pasiënte met antifungale medisyne behandel kan word.'

Navorsers het hom met antifungale medisyne behandel

Dinge was nie dieselfde vir die man nadat hy 'n kursus antibiotika voltooi het om 'n duimbesering te behandel nie. Sy persoonlikheid het begin verander, het navorsers in die studie geskryf, en hy het episodes van depressie, 'breinmis', geheueverlies en aggressiewe gedrag ervaar wat vir hom uiters karaktervol was.

Drie jaar later, na sy vermeende dronkbestuur -arrestasie, het die man se tante 'n blaasmasjien gekoop om sy alkoholvlakke op te teken. Sy het gehoor van 'n soortgelyke geval wat suksesvol deur 'n dokter in Ohio behandel is en haar neef oortuig om ook daar behandeling te soek.

Sy basiese laboratoriumtoetse was normaal. Maar dokters het twee stamme gis in sy stoelgang gevind: Saccharomyces cerevisiae, 'n gis wat algemeen gebruik word by bierbrou, wynmaak en bak, asook 'n ander swam.

Die man is suksesvol in die kliniek in Ohio behandel en aangesê om by 'n streng koolhidraatvrye dieet te bly, asook spesiale aanvullings. Maar na 'n paar weke het sy simptome weer begin opvlam. Hierdie keer het dit gelyk asof geen behandeling werk nie, ondanks besoeke aan talle mediese spesialiste.

Op 'n stadium het die man so dronk geword dat hy geval en bloeding in sy brein ondervind het. Hy is na 'n neurochirurgiese sentrum geneem waar hy binne 10 dae spontaan herstel het, het navorsers gesê.

'In hierdie instelling het sy bloedalkoholvlakke gewissel van 50 tot 400 mg/dL,' het die navorsers geskryf. "Ook hier het die mediese personeel geweier om te glo dat hy ondanks sy volgehoue ​​ontkenning nie alkohol gedrink het nie."

Uiteindelik het die man hulp by 'n aanlyn ondersteuningsgroep gesoek en met die navorsers van die Richmond University Medical Center in verbinding getree, wat in die studie gesê het dat hulle glo dat die antibiotika wat hy jare gelede geneem het, sy derm mikrobioom verander en dat swamme in sy spysverteringskanaal.

Die navorsers het daarna antifungale terapieë en probiotika gebruik om die bakterieë in sy ingewande te normaliseer, 'n behandeling wat hy voortgesit het. En afgesien van 'n terugval wat plaasgevind het nadat hy pizza en koeldrank gebyt het sonder om die navorsers te vertel, lyk dit asof dit werk.

En hy kan weer pizza eet.

'Ongeveer 1,5 jaar later bly hy asimptomaties en het hy sy vorige lewenstyl hervat, insluitend die eet van 'n normale dieet, terwyl hy nog steeds sy asemhaling alkohol sporadies nagaan', het die skrywers in die studie geskryf.

Die toestand word selde gediagnoseer

Daar is slegs 'n paar studies wat gevalle van dermfermentasiesindroom beskryf en die toestand word selde gediagnoseer, het Malik gesê. In die verlede is dit selfs as 'n mite beskou.

Darmgistesindroom word in 1912 beskryf as 'kiemkoolhidraatfermentasie', en is in die 1930's en 1940's bestudeer as 'n bydraende faktor tot vitamientekorte en prikkelbare dermsindroom. 'N Groep van 20 tot 30 gevalle het in die sewentigerjare in Japan verskyn en die eerste Amerikaanse gevalle is ongeveer 10 jaar later aangemeld.

Daar was die afgelope paar jaar 'n handjievol aangemelde gevalle. 'N 2013-studie beskryf 'n geval van 'n 61-jarige man wat jare lank altyd dronk was voordat hy met die dermfermentasiesindroom gediagnoseer is. In 2015 het 'n DUI van 'n vrou in die staat New York ontslaan nadat sy bewys gelewer het dat sy die toestand het.

Die skrywers van die studie van die Richmond University Medical Center beveel dokters aan om ondersoek in te stel na die toestand, veral as 'n pasiënt 'n verhoogde alkoholgehalte in die bloed toon ondanks die ontkenning dat hy alkohol gebruik het.

Die vroeë tekens van dermfermentasiesindroom kan gemoedsveranderinge, delirium en breinmis insluit, het die navorsers geskryf, selfs voordat 'n pasiënt simptome van alkoholverslawing begin toon.

Die studie sê meer navorsing moet gedoen word oor die gebruik van probiotika as 'n behandeling vir die toestand.

'Dit is 'n toestand wat behandel kan word met dieetaanpassings, gepaste antifungale terapie en moontlik probiotika,' het die navorsers geskryf. "Die gebruik van probiotika en fekale mikrobiota -oorplanting kan oorweeg word vir toekomstige studies."

Die-CNN-draad
™ en amp © 2019 Cable News Network, Inc., 'n WarnerMedia -onderneming. Alle regte voorbehou.


Navorsers ontdek dat die mens se liggaam alkohol produseer

(CNN) - Toe 'n man in Noord -Carolina afgetrek word omdat hy vermoedelik dronk bestuur het, het die polisie hom nie geglo toe hy gesê het dat hy nie alkohol gehad het nie.

Die man, destyds in die laat veertigerjare, het geweier om 'n asemtoets te neem en is na 'n hospitaal geneem, waar sy aanvanklike bloedalkoholvlak 0.2% was - ongeveer 2.5 keer die wettige limiet en die ekwivalent van die gebruik van 10 drankies n uur. Ten spyte daarvan dat die man op en af ​​sweer dat hy niks gehad het om te drink nie, het dokters hom ook nie geglo nie.

Maar navorsers van die Richmond University Medical Center in New York het uiteindelik ontdek dat die man die waarheid praat. Hy het nie bier of skemerkelkies laat sak nie - in plaas daarvan was daar gis in sy ingewande wat waarskynlik koolhidrate in die kos wat hy geëet het, kon verander na alkohol.

Met ander woorde, sy liggaam was besig om bier te brou.

Die bevindings is gerapporteer in 'n studie in BMJ Open Gastroenterology. Die man, wie se identiteit nie bekend gemaak is nie, het 'n selde gediagnoseerde mediese toestand genaamd auto-brouery sindroom (ABS), ook bekend as dermfermentasiesindroom.

Darmgistingsindroom kom voor wanneer gis in die spysverteringskanaal veroorsaak dat die liggaam koolhidrate wat deur voedsel ingeneem word, omskakel in alkohol. Die proses vind gewoonlik plaas in die boonste GI -kanaal, wat die maag en die eerste deel van die dunderm insluit.

"Hierdie pasiënte het presies dieselfde implikasies van alkoholisme: die reuk, die asemhaling, slaperigheid, gangveranderinge," het Fahad Malik, hoofskrywer van die studie en die hoof inwoner van die interne geneeskunde aan die Universiteit van Alabama in Birmingham, aan CNN gesê. 'Hulle sal verskyn as iemand wat dronk is deur alkohol, maar die enigste verskil hier is dat hierdie pasiënte met antifungale medisyne behandel kan word.'

Navorsers het hom met antifungale medisyne behandel

Dinge was nie dieselfde vir die man nadat hy 'n kursus antibiotika voltooi het om 'n duimbesering te behandel nie. Sy persoonlikheid het begin verander, het navorsers in die studie geskryf, en hy het episodes van depressie, 'breinmis', geheueverlies en aggressiewe gedrag ervaar wat vir hom uiters karaktervol was.

Drie jaar later, na sy vermeende dronkbestuur -arrestasie, het die man se tante 'n blaasmasjien gekoop om sy alkoholvlakke op te teken. Sy het gehoor van 'n soortgelyke geval wat suksesvol deur 'n dokter in Ohio behandel is en haar neef oortuig om ook daar behandeling te soek.

Sy basiese laboratoriumtoetse was normaal. Maar dokters het twee stamme gis in sy stoelgang gevind: Saccharomyces cerevisiae, 'n gis wat algemeen gebruik word by bierbrou, wynmaak en bak, asook 'n ander swam.

Die man is suksesvol in die kliniek in Ohio behandel en aangesê om by 'n streng koolhidraatvrye dieet te bly, asook spesiale aanvullings. Maar na 'n paar weke het sy simptome weer begin opvlam. Hierdie keer het dit gelyk asof geen behandeling werk nie, ondanks besoeke aan talle mediese spesialiste.

Op 'n stadium het die man so dronk geword dat hy geval en bloeding in sy brein ondervind het. Hy is na 'n neurochirurgiese sentrum geneem waar hy binne 10 dae spontaan herstel het, het navorsers gesê.

'In hierdie instelling het sy bloedalkoholvlakke gewissel van 50 tot 400 mg/dL,' het die navorsers geskryf. "Ook hier het die mediese personeel geweier om te glo dat hy ondanks sy volgehoue ​​ontkenning nie alkohol gedrink het nie."

Uiteindelik het die man hulp by 'n aanlyn ondersteuningsgroep gesoek en met die navorsers van die Richmond University Medical Center in verbinding getree, wat in die studie gesê het dat hulle glo dat die antibiotika wat hy jare gelede geneem het, sy derm mikrobioom verander en dat swamme in sy spysverteringskanaal.

Die navorsers het daarna antifungale terapieë en probiotika gebruik om die bakterieë in sy ingewande te normaliseer, 'n behandeling wat hy voortgesit het. En afgesien van 'n terugval wat plaasgevind het nadat hy pizza en koeldrank gebyt het sonder om die navorsers te vertel, lyk dit asof dit werk.

En hy kan weer pizza eet.

'Ongeveer 1,5 jaar later bly hy asimptomaties en het hy sy vorige lewenstyl hervat, insluitend die eet van 'n normale dieet, terwyl hy nog steeds sy asemhaling alkohol sporadies nagaan', het die skrywers in die studie geskryf.

Die toestand word selde gediagnoseer

Daar is slegs 'n paar studies wat gevalle van dermfermentasiesindroom beskryf en die toestand word selde gediagnoseer, het Malik gesê. In die verlede is dit selfs as 'n mite beskou.

Darmgistesindroom word in 1912 beskryf as 'kiemkoolhidraatfermentasie', en is in die 1930's en 1940's bestudeer as 'n bydraende faktor tot vitamientekorte en prikkelbare dermsindroom. 'N Groep van 20 tot 30 gevalle het in die sewentigerjare in Japan verskyn en die eerste Amerikaanse gevalle is ongeveer 10 jaar later aangemeld.

Daar was die afgelope paar jaar 'n handjievol aangemelde gevalle. 'N 2013-studie beskryf 'n geval van 'n 61-jarige man wat jare lank altyd dronk was voordat hy met die dermfermentasiesindroom gediagnoseer is. In 2015 het 'n DUI van 'n vrou in die staat New York ontslaan nadat sy bewys gelewer het dat sy die toestand het.

Die skrywers van die studie van die Richmond University Medical Center beveel dokters aan om ondersoek in te stel na die toestand, veral as 'n pasiënt 'n verhoogde alkoholgehalte in die bloed toon ondanks die ontkenning dat hy alkohol gebruik het.

Die vroeë tekens van dermfermentasiesindroom kan gemoedsveranderinge, delirium en breinmis insluit, het die navorsers geskryf, selfs voordat 'n pasiënt simptome van alkoholverslawing begin toon.

Die studie sê meer navorsing moet gedoen word oor die gebruik van probiotika as 'n behandeling vir die toestand.

"This is a condition that is treatable with dietary modifications, appropriate antifungal therapy, and possibly probiotics," the researchers wrote. "The use of probiotics and faecal microbiota transplantation could be considered for future studies."

The-CNN-Wire
™ & © 2019 Cable News Network, Inc., a WarnerMedia Company. Alle regte voorbehou.


Researchers discover that man's body was producing alcohol

(CNN) -- When a man in North Carolina was pulled over on suspicion of driving drunk, police didn't believe him when he said he hadn't had any alcohol.

The man, in his late 40's at the time, refused to take a breathalyzer test and was taken to a hospital, where his initial blood alcohol level was found to be 0.2% — about 2.5 times the legal limit and the equivalent of consuming 10 drinks an hour. Despite the man swearing up and down that he hadn't had anything to drink, doctors didn't believe him either.

But researchers at the Richmond University Medical Center in New York eventually discovered that the man was telling the truth. He wasn't downing beers or cocktails — instead, there was yeast in his gut that was likely converting carbohydrates in the food he ate to alcohol.

In other words, his body was brewing beer.

The findings were reported in a study in BMJ Open Gastroenterology. The man, whose identity has not been revealed, had a rarely diagnosed medical condition called auto-brewery syndrome (ABS), also known as gut fermentation syndrome.

Gut fermentation syndrome occurs when yeast in the gastrointestinal tract causes the body to convert carbohydrates ingested through food into alcohol. The process typically takes place in the upper GI tract, which includes the stomach and the first part of the small intestine.

"These patients have the exact same implications of alcoholism: the smell, the breath, drowsiness, gait changes," Fahad Malik, the study's lead author and the chief internal medicine resident at the University of Alabama at Birmingham, told CNN. "They will present as someone who's intoxicated by alcohol, but the only difference here is that these patients can be treated by antifungal medications."

Researchers treated him with antifungal medications

Things weren't the same for the man after he completed a course of antibiotics to treat a thumb injury. His personality started to change, researchers wrote in the study, and he experienced episodes of depression, 'brain fog,' memory loss and aggressive behavior that was out of character for him.

Three years later, after his suspected drunk driving arrest, the man's aunt bought a breathalyzer to record his alcohol levels. She had heard about a similar case that had been successfully treated by a doctor in Ohio and convinced her nephew to seek treatment there too.

His basic lab tests turned out normal. But doctors found two strains of yeast in his stool: Saccharomyces cerevisiae, a yeast commonly used in beer brewing, winemaking and baking, as well as another fungus.

The man was successfully treated at the Ohio clinic and told to stick to a strict carbohydrate-free diet along with some special supplements. But after a few weeks, his symptoms started to flare up again. This time, no treatment seemed to work despite visits to numerous medical professionals.

At one point, the man became so inebriated that he fell and experienced bleeding in his brain. He was taken to a neurosurgical center where he spontaneously recovered in 10 days, researchers said.

"In this institution, his blood alcohol levels ranged from 50 to 400 mg/dL," the researchers wrote. "Here too, the medical staff refused to believe that he did not drink alcohol despite his persistent denials."

Finally, the man sought help from an online support group and got in touch with the researchers at the Richmond University Medical Center, who said in the study that they believed the antibiotics he took years ago altered his gut microbiome and allowed fungi to grow in his gastrointestinal tract.

The researchers then used antifungal therapies and probiotics to help normalize the bacteria in his gut, a treatment that he has continued. And aside from one relapse that occurred after he binged on pizza and soda without telling the researchers, it seems to be working.

And he can eat pizza again.

"Approximately 1.5 years later, he remains asymptomatic and has resumed his previous lifestyle, including eating a normal diet while still checking his breath alcohol levels sporadically," the authors wrote in the study.

The condition is rarely diagnosed

There have only been a few studies documenting cases of gut fermentation syndrome and the condition is rarely diagnosed, Malik said. In the past, it's even been regarded as a myth.

Gut fermentation syndrome was described in 1912 as "germ carbohydrate fermentation," and was studied in the 1930s and 1940s as a contributing factor to vitamin deficiencies and irritable bowel syndrome. A group of 20 to 30 cases popped up in Japan in the 1970s and the first US cases were reported about 10 years later.

There have been a handful of reported cases in recent years. A 2013 study described a case of a 61-year-old man who for years seemed to be drunk all the time before he was diagnosed with gut fermentation syndrome. In 2015, a woman in upstate New York had a DUI dismissed after presenting evidence that she had the condition.

The authors of the Richmond University Medical Center study recommend that doctors investigate for the condition especially when a patient shows elevated blood alcohol levels despite denying that they consumed alcohol.

Early signs of gut fermentation syndrome can include mood changes, delirium and brain fog, the researchers wrote, even before a patient starts exhibiting symptoms of alcohol inebriation.

The study says more research should be done on the use of probiotics as a treatment for the condition.

"This is a condition that is treatable with dietary modifications, appropriate antifungal therapy, and possibly probiotics," the researchers wrote. "The use of probiotics and faecal microbiota transplantation could be considered for future studies."

The-CNN-Wire
™ & © 2019 Cable News Network, Inc., a WarnerMedia Company. Alle regte voorbehou.


Researchers discover that man's body was producing alcohol

(CNN) -- When a man in North Carolina was pulled over on suspicion of driving drunk, police didn't believe him when he said he hadn't had any alcohol.

The man, in his late 40's at the time, refused to take a breathalyzer test and was taken to a hospital, where his initial blood alcohol level was found to be 0.2% — about 2.5 times the legal limit and the equivalent of consuming 10 drinks an hour. Despite the man swearing up and down that he hadn't had anything to drink, doctors didn't believe him either.

But researchers at the Richmond University Medical Center in New York eventually discovered that the man was telling the truth. He wasn't downing beers or cocktails — instead, there was yeast in his gut that was likely converting carbohydrates in the food he ate to alcohol.

In other words, his body was brewing beer.

The findings were reported in a study in BMJ Open Gastroenterology. The man, whose identity has not been revealed, had a rarely diagnosed medical condition called auto-brewery syndrome (ABS), also known as gut fermentation syndrome.

Gut fermentation syndrome occurs when yeast in the gastrointestinal tract causes the body to convert carbohydrates ingested through food into alcohol. The process typically takes place in the upper GI tract, which includes the stomach and the first part of the small intestine.

"These patients have the exact same implications of alcoholism: the smell, the breath, drowsiness, gait changes," Fahad Malik, the study's lead author and the chief internal medicine resident at the University of Alabama at Birmingham, told CNN. "They will present as someone who's intoxicated by alcohol, but the only difference here is that these patients can be treated by antifungal medications."

Researchers treated him with antifungal medications

Things weren't the same for the man after he completed a course of antibiotics to treat a thumb injury. His personality started to change, researchers wrote in the study, and he experienced episodes of depression, 'brain fog,' memory loss and aggressive behavior that was out of character for him.

Three years later, after his suspected drunk driving arrest, the man's aunt bought a breathalyzer to record his alcohol levels. She had heard about a similar case that had been successfully treated by a doctor in Ohio and convinced her nephew to seek treatment there too.

His basic lab tests turned out normal. But doctors found two strains of yeast in his stool: Saccharomyces cerevisiae, a yeast commonly used in beer brewing, winemaking and baking, as well as another fungus.

The man was successfully treated at the Ohio clinic and told to stick to a strict carbohydrate-free diet along with some special supplements. But after a few weeks, his symptoms started to flare up again. This time, no treatment seemed to work despite visits to numerous medical professionals.

At one point, the man became so inebriated that he fell and experienced bleeding in his brain. He was taken to a neurosurgical center where he spontaneously recovered in 10 days, researchers said.

"In this institution, his blood alcohol levels ranged from 50 to 400 mg/dL," the researchers wrote. "Here too, the medical staff refused to believe that he did not drink alcohol despite his persistent denials."

Finally, the man sought help from an online support group and got in touch with the researchers at the Richmond University Medical Center, who said in the study that they believed the antibiotics he took years ago altered his gut microbiome and allowed fungi to grow in his gastrointestinal tract.

The researchers then used antifungal therapies and probiotics to help normalize the bacteria in his gut, a treatment that he has continued. And aside from one relapse that occurred after he binged on pizza and soda without telling the researchers, it seems to be working.

And he can eat pizza again.

"Approximately 1.5 years later, he remains asymptomatic and has resumed his previous lifestyle, including eating a normal diet while still checking his breath alcohol levels sporadically," the authors wrote in the study.

The condition is rarely diagnosed

There have only been a few studies documenting cases of gut fermentation syndrome and the condition is rarely diagnosed, Malik said. In the past, it's even been regarded as a myth.

Gut fermentation syndrome was described in 1912 as "germ carbohydrate fermentation," and was studied in the 1930s and 1940s as a contributing factor to vitamin deficiencies and irritable bowel syndrome. A group of 20 to 30 cases popped up in Japan in the 1970s and the first US cases were reported about 10 years later.

There have been a handful of reported cases in recent years. A 2013 study described a case of a 61-year-old man who for years seemed to be drunk all the time before he was diagnosed with gut fermentation syndrome. In 2015, a woman in upstate New York had a DUI dismissed after presenting evidence that she had the condition.

The authors of the Richmond University Medical Center study recommend that doctors investigate for the condition especially when a patient shows elevated blood alcohol levels despite denying that they consumed alcohol.

Early signs of gut fermentation syndrome can include mood changes, delirium and brain fog, the researchers wrote, even before a patient starts exhibiting symptoms of alcohol inebriation.

The study says more research should be done on the use of probiotics as a treatment for the condition.

"This is a condition that is treatable with dietary modifications, appropriate antifungal therapy, and possibly probiotics," the researchers wrote. "The use of probiotics and faecal microbiota transplantation could be considered for future studies."

The-CNN-Wire
™ & © 2019 Cable News Network, Inc., a WarnerMedia Company. Alle regte voorbehou.


Researchers discover that man's body was producing alcohol

(CNN) -- When a man in North Carolina was pulled over on suspicion of driving drunk, police didn't believe him when he said he hadn't had any alcohol.

The man, in his late 40's at the time, refused to take a breathalyzer test and was taken to a hospital, where his initial blood alcohol level was found to be 0.2% — about 2.5 times the legal limit and the equivalent of consuming 10 drinks an hour. Despite the man swearing up and down that he hadn't had anything to drink, doctors didn't believe him either.

But researchers at the Richmond University Medical Center in New York eventually discovered that the man was telling the truth. He wasn't downing beers or cocktails — instead, there was yeast in his gut that was likely converting carbohydrates in the food he ate to alcohol.

In other words, his body was brewing beer.

The findings were reported in a study in BMJ Open Gastroenterology. The man, whose identity has not been revealed, had a rarely diagnosed medical condition called auto-brewery syndrome (ABS), also known as gut fermentation syndrome.

Gut fermentation syndrome occurs when yeast in the gastrointestinal tract causes the body to convert carbohydrates ingested through food into alcohol. The process typically takes place in the upper GI tract, which includes the stomach and the first part of the small intestine.

"These patients have the exact same implications of alcoholism: the smell, the breath, drowsiness, gait changes," Fahad Malik, the study's lead author and the chief internal medicine resident at the University of Alabama at Birmingham, told CNN. "They will present as someone who's intoxicated by alcohol, but the only difference here is that these patients can be treated by antifungal medications."

Researchers treated him with antifungal medications

Things weren't the same for the man after he completed a course of antibiotics to treat a thumb injury. His personality started to change, researchers wrote in the study, and he experienced episodes of depression, 'brain fog,' memory loss and aggressive behavior that was out of character for him.

Three years later, after his suspected drunk driving arrest, the man's aunt bought a breathalyzer to record his alcohol levels. She had heard about a similar case that had been successfully treated by a doctor in Ohio and convinced her nephew to seek treatment there too.

His basic lab tests turned out normal. But doctors found two strains of yeast in his stool: Saccharomyces cerevisiae, a yeast commonly used in beer brewing, winemaking and baking, as well as another fungus.

The man was successfully treated at the Ohio clinic and told to stick to a strict carbohydrate-free diet along with some special supplements. But after a few weeks, his symptoms started to flare up again. This time, no treatment seemed to work despite visits to numerous medical professionals.

At one point, the man became so inebriated that he fell and experienced bleeding in his brain. He was taken to a neurosurgical center where he spontaneously recovered in 10 days, researchers said.

"In this institution, his blood alcohol levels ranged from 50 to 400 mg/dL," the researchers wrote. "Here too, the medical staff refused to believe that he did not drink alcohol despite his persistent denials."

Finally, the man sought help from an online support group and got in touch with the researchers at the Richmond University Medical Center, who said in the study that they believed the antibiotics he took years ago altered his gut microbiome and allowed fungi to grow in his gastrointestinal tract.

The researchers then used antifungal therapies and probiotics to help normalize the bacteria in his gut, a treatment that he has continued. And aside from one relapse that occurred after he binged on pizza and soda without telling the researchers, it seems to be working.

And he can eat pizza again.

"Approximately 1.5 years later, he remains asymptomatic and has resumed his previous lifestyle, including eating a normal diet while still checking his breath alcohol levels sporadically," the authors wrote in the study.

The condition is rarely diagnosed

There have only been a few studies documenting cases of gut fermentation syndrome and the condition is rarely diagnosed, Malik said. In the past, it's even been regarded as a myth.

Gut fermentation syndrome was described in 1912 as "germ carbohydrate fermentation," and was studied in the 1930s and 1940s as a contributing factor to vitamin deficiencies and irritable bowel syndrome. A group of 20 to 30 cases popped up in Japan in the 1970s and the first US cases were reported about 10 years later.

There have been a handful of reported cases in recent years. A 2013 study described a case of a 61-year-old man who for years seemed to be drunk all the time before he was diagnosed with gut fermentation syndrome. In 2015, a woman in upstate New York had a DUI dismissed after presenting evidence that she had the condition.

The authors of the Richmond University Medical Center study recommend that doctors investigate for the condition especially when a patient shows elevated blood alcohol levels despite denying that they consumed alcohol.

Early signs of gut fermentation syndrome can include mood changes, delirium and brain fog, the researchers wrote, even before a patient starts exhibiting symptoms of alcohol inebriation.

The study says more research should be done on the use of probiotics as a treatment for the condition.

"This is a condition that is treatable with dietary modifications, appropriate antifungal therapy, and possibly probiotics," the researchers wrote. "The use of probiotics and faecal microbiota transplantation could be considered for future studies."

The-CNN-Wire
™ & © 2019 Cable News Network, Inc., a WarnerMedia Company. Alle regte voorbehou.


Researchers discover that man's body was producing alcohol

(CNN) -- When a man in North Carolina was pulled over on suspicion of driving drunk, police didn't believe him when he said he hadn't had any alcohol.

The man, in his late 40's at the time, refused to take a breathalyzer test and was taken to a hospital, where his initial blood alcohol level was found to be 0.2% — about 2.5 times the legal limit and the equivalent of consuming 10 drinks an hour. Despite the man swearing up and down that he hadn't had anything to drink, doctors didn't believe him either.

But researchers at the Richmond University Medical Center in New York eventually discovered that the man was telling the truth. He wasn't downing beers or cocktails — instead, there was yeast in his gut that was likely converting carbohydrates in the food he ate to alcohol.

In other words, his body was brewing beer.

The findings were reported in a study in BMJ Open Gastroenterology. The man, whose identity has not been revealed, had a rarely diagnosed medical condition called auto-brewery syndrome (ABS), also known as gut fermentation syndrome.

Gut fermentation syndrome occurs when yeast in the gastrointestinal tract causes the body to convert carbohydrates ingested through food into alcohol. The process typically takes place in the upper GI tract, which includes the stomach and the first part of the small intestine.

"These patients have the exact same implications of alcoholism: the smell, the breath, drowsiness, gait changes," Fahad Malik, the study's lead author and the chief internal medicine resident at the University of Alabama at Birmingham, told CNN. "They will present as someone who's intoxicated by alcohol, but the only difference here is that these patients can be treated by antifungal medications."

Researchers treated him with antifungal medications

Things weren't the same for the man after he completed a course of antibiotics to treat a thumb injury. His personality started to change, researchers wrote in the study, and he experienced episodes of depression, 'brain fog,' memory loss and aggressive behavior that was out of character for him.

Three years later, after his suspected drunk driving arrest, the man's aunt bought a breathalyzer to record his alcohol levels. She had heard about a similar case that had been successfully treated by a doctor in Ohio and convinced her nephew to seek treatment there too.

His basic lab tests turned out normal. But doctors found two strains of yeast in his stool: Saccharomyces cerevisiae, a yeast commonly used in beer brewing, winemaking and baking, as well as another fungus.

The man was successfully treated at the Ohio clinic and told to stick to a strict carbohydrate-free diet along with some special supplements. But after a few weeks, his symptoms started to flare up again. This time, no treatment seemed to work despite visits to numerous medical professionals.

At one point, the man became so inebriated that he fell and experienced bleeding in his brain. He was taken to a neurosurgical center where he spontaneously recovered in 10 days, researchers said.

"In this institution, his blood alcohol levels ranged from 50 to 400 mg/dL," the researchers wrote. "Here too, the medical staff refused to believe that he did not drink alcohol despite his persistent denials."

Finally, the man sought help from an online support group and got in touch with the researchers at the Richmond University Medical Center, who said in the study that they believed the antibiotics he took years ago altered his gut microbiome and allowed fungi to grow in his gastrointestinal tract.

The researchers then used antifungal therapies and probiotics to help normalize the bacteria in his gut, a treatment that he has continued. And aside from one relapse that occurred after he binged on pizza and soda without telling the researchers, it seems to be working.

And he can eat pizza again.

"Approximately 1.5 years later, he remains asymptomatic and has resumed his previous lifestyle, including eating a normal diet while still checking his breath alcohol levels sporadically," the authors wrote in the study.

The condition is rarely diagnosed

There have only been a few studies documenting cases of gut fermentation syndrome and the condition is rarely diagnosed, Malik said. In the past, it's even been regarded as a myth.

Gut fermentation syndrome was described in 1912 as "germ carbohydrate fermentation," and was studied in the 1930s and 1940s as a contributing factor to vitamin deficiencies and irritable bowel syndrome. A group of 20 to 30 cases popped up in Japan in the 1970s and the first US cases were reported about 10 years later.

There have been a handful of reported cases in recent years. A 2013 study described a case of a 61-year-old man who for years seemed to be drunk all the time before he was diagnosed with gut fermentation syndrome. In 2015, a woman in upstate New York had a DUI dismissed after presenting evidence that she had the condition.

The authors of the Richmond University Medical Center study recommend that doctors investigate for the condition especially when a patient shows elevated blood alcohol levels despite denying that they consumed alcohol.

Early signs of gut fermentation syndrome can include mood changes, delirium and brain fog, the researchers wrote, even before a patient starts exhibiting symptoms of alcohol inebriation.

The study says more research should be done on the use of probiotics as a treatment for the condition.

"This is a condition that is treatable with dietary modifications, appropriate antifungal therapy, and possibly probiotics," the researchers wrote. "The use of probiotics and faecal microbiota transplantation could be considered for future studies."

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™ & © 2019 Cable News Network, Inc., a WarnerMedia Company. Alle regte voorbehou.


Researchers discover that man's body was producing alcohol

(CNN) -- When a man in North Carolina was pulled over on suspicion of driving drunk, police didn't believe him when he said he hadn't had any alcohol.

The man, in his late 40's at the time, refused to take a breathalyzer test and was taken to a hospital, where his initial blood alcohol level was found to be 0.2% — about 2.5 times the legal limit and the equivalent of consuming 10 drinks an hour. Despite the man swearing up and down that he hadn't had anything to drink, doctors didn't believe him either.

But researchers at the Richmond University Medical Center in New York eventually discovered that the man was telling the truth. He wasn't downing beers or cocktails — instead, there was yeast in his gut that was likely converting carbohydrates in the food he ate to alcohol.

In other words, his body was brewing beer.

The findings were reported in a study in BMJ Open Gastroenterology. The man, whose identity has not been revealed, had a rarely diagnosed medical condition called auto-brewery syndrome (ABS), also known as gut fermentation syndrome.

Gut fermentation syndrome occurs when yeast in the gastrointestinal tract causes the body to convert carbohydrates ingested through food into alcohol. The process typically takes place in the upper GI tract, which includes the stomach and the first part of the small intestine.

"These patients have the exact same implications of alcoholism: the smell, the breath, drowsiness, gait changes," Fahad Malik, the study's lead author and the chief internal medicine resident at the University of Alabama at Birmingham, told CNN. "They will present as someone who's intoxicated by alcohol, but the only difference here is that these patients can be treated by antifungal medications."

Researchers treated him with antifungal medications

Things weren't the same for the man after he completed a course of antibiotics to treat a thumb injury. His personality started to change, researchers wrote in the study, and he experienced episodes of depression, 'brain fog,' memory loss and aggressive behavior that was out of character for him.

Three years later, after his suspected drunk driving arrest, the man's aunt bought a breathalyzer to record his alcohol levels. She had heard about a similar case that had been successfully treated by a doctor in Ohio and convinced her nephew to seek treatment there too.

His basic lab tests turned out normal. But doctors found two strains of yeast in his stool: Saccharomyces cerevisiae, a yeast commonly used in beer brewing, winemaking and baking, as well as another fungus.

The man was successfully treated at the Ohio clinic and told to stick to a strict carbohydrate-free diet along with some special supplements. But after a few weeks, his symptoms started to flare up again. This time, no treatment seemed to work despite visits to numerous medical professionals.

At one point, the man became so inebriated that he fell and experienced bleeding in his brain. He was taken to a neurosurgical center where he spontaneously recovered in 10 days, researchers said.

"In this institution, his blood alcohol levels ranged from 50 to 400 mg/dL," the researchers wrote. "Here too, the medical staff refused to believe that he did not drink alcohol despite his persistent denials."

Finally, the man sought help from an online support group and got in touch with the researchers at the Richmond University Medical Center, who said in the study that they believed the antibiotics he took years ago altered his gut microbiome and allowed fungi to grow in his gastrointestinal tract.

The researchers then used antifungal therapies and probiotics to help normalize the bacteria in his gut, a treatment that he has continued. And aside from one relapse that occurred after he binged on pizza and soda without telling the researchers, it seems to be working.

And he can eat pizza again.

"Approximately 1.5 years later, he remains asymptomatic and has resumed his previous lifestyle, including eating a normal diet while still checking his breath alcohol levels sporadically," the authors wrote in the study.

The condition is rarely diagnosed

There have only been a few studies documenting cases of gut fermentation syndrome and the condition is rarely diagnosed, Malik said. In the past, it's even been regarded as a myth.

Gut fermentation syndrome was described in 1912 as "germ carbohydrate fermentation," and was studied in the 1930s and 1940s as a contributing factor to vitamin deficiencies and irritable bowel syndrome. A group of 20 to 30 cases popped up in Japan in the 1970s and the first US cases were reported about 10 years later.

There have been a handful of reported cases in recent years. A 2013 study described a case of a 61-year-old man who for years seemed to be drunk all the time before he was diagnosed with gut fermentation syndrome. In 2015, a woman in upstate New York had a DUI dismissed after presenting evidence that she had the condition.

The authors of the Richmond University Medical Center study recommend that doctors investigate for the condition especially when a patient shows elevated blood alcohol levels despite denying that they consumed alcohol.

Early signs of gut fermentation syndrome can include mood changes, delirium and brain fog, the researchers wrote, even before a patient starts exhibiting symptoms of alcohol inebriation.

The study says more research should be done on the use of probiotics as a treatment for the condition.

"This is a condition that is treatable with dietary modifications, appropriate antifungal therapy, and possibly probiotics," the researchers wrote. "The use of probiotics and faecal microbiota transplantation could be considered for future studies."

The-CNN-Wire
™ & © 2019 Cable News Network, Inc., a WarnerMedia Company. Alle regte voorbehou.


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